So it could be shocking to find out they have an effect on bodybuilding physiques. Painkillers such as aspirin has been a part of normal life for many in the world. This will allow the benefits of training to take their effect – if you still feel pain after that, the drugs will do their job reducing inflammation with little damage to your muscle growth. If you are going to use pain killers like NSAIDs to reduce pain – simply wait at least four to five hours before taking an aspirin. However, if you want to be safe rather than sorry, Brainum has some advice to avoid any negative ramifications. This study also would need further research and follow up to become more reliable. Ultimately, Jerry Brainum believes that the affect NSAIDs have on muscle hypertrophy is too minimal to truly kill gains. So should bodybuilders avoid NSAIDs like Aspirin? The NSAIDs likely do still block muscle hypertrophy – but for older individuals the benefit of reducing systemic inflammation leads to more optimal workouts. The contradiction between younger and older individuals in this study is not a mistake. So what does this have to do with NSAIDs? It seems that the reason older individuals experienced an increase in muscle growth while using NSAIDs comes down to the benefits of reducing systemic inflammation. It can literally stave off this systemic inflammation and make you a more able and mobile older individual. ![]() It’s the reason why we have the stereotype, “Help, I’ve fallen and I can’t get up!” Typically, it’s vital for those growing order to add resistance training to their health regiment. This kind of inflammation can get so bad that it leads to very serious conditions in old age. ![]() Jerry Brainum explains that as we get older, we start to experience systemic inflammation. On the flip side, older individuals (50+) showcased an increase in muscle growth upon using NSAIDs. A study showed that young adult subjects (20s and 30s) had an increase in muscle mass and hypertrophy upon using NSAIDs. To add to the confusion, there also seem to be conflicting studies depending on the age of the individual. With each passing decade, the scientific community discovers new findings that change their outlook on these drugs. In fact, there have been studies in the past that claimed the same thing – only for newer studies to deny it. However, Jerry Brainum points out that the medical communities relationship with NSAID substances has always been a roller coaster. Do NSAID pain relief drugs reduce muscle hypertrophy?īased on a recent study, it does appear that NSAID drugs do slightly block muscle hypertrophy. Do these drugs actually reduce gains? Jerry Brainum, being passionate in the bodybuilding community, decided to use his knowledge to put the study to the test – and see if these findings will really have an affect on a bodybuilder’s lifestyle. That sentence alone will make serous lifters and bodybuilders shudder with fear. However, a recent study seems to show that NSAIDs have a side effect that reduces muscle hypertrophy and protein synthesis. It’s been a household staple for decades. Nearly all of us had turned NSAIDs at one point or another – whether to reduce a headache or a sore body part. Aspirin and Ibuprofen would fall under this category. On the other end of the spectrum you have anti-inflammatory pain killers – these are called NSAIDs in the medical community. ![]() The ones that make headlines most often these days are opiates due to their addictive nature and the massive health concern they’ve called. There are a wide variety of pain reducing drugs on the market. Should this be a real concern for serious bodybuilders? In our latest episode of Straight Facts, Jerry Brainum breaks down NSAID painkillers and whether or not they could be hurting gains in bodybuilding. But recent studies show that drugs like aspirin may be blocking muscle hypertrophy. So it’s common for bodybuilders to use over the counter pain killers like aspirin to help reduce soreness, aches, and pains. While most will always aim to avoid serious injuries like a pec tear, wear and tear is unavoidable. When training seriously in the gym for size and strength – it’s inevitable that pain and injuries will occur. Jerry Brainum breaks down recent studies that seem to prove certain pain killers block hypertrophy and muscle protein synthesis.
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